node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmc1_0002 | Mmc1_2541 | Mmc1_0002 | Mmc1_2541 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: pfo:Pfl_3001 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, Zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.684 |
Mmc1_0002 | mutL | Mmc1_0002 | Mmc1_1040 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.893 |
Mmc1_0002 | mutS | Mmc1_0002 | Mmc1_1449 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.980 |
Mmc1_0002 | polA | Mmc1_0002 | Mmc1_3261 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.998 |
Mmc1_0002 | topA | Mmc1_0002 | Mmc1_3660 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.684 |
Mmc1_0257 | mutL | Mmc1_0257 | Mmc1_1040 | PFAM: DNA repair protein RadC; KEGG: det:DET1462 DNA repair protein, RadC family; Belongs to the UPF0758 family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.542 |
Mmc1_0257 | mutS | Mmc1_0257 | Mmc1_1449 | PFAM: DNA repair protein RadC; KEGG: det:DET1462 DNA repair protein, RadC family; Belongs to the UPF0758 family. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.606 |
Mmc1_1445 | Mmc1_1447 | Mmc1_1445 | Mmc1_1447 | PFAM: protein of unknown function DUF107; KEGG: pfl:PFL_5949 hypothetical protein. | KEGG: rru:Rru_A2420 transferase hexapeptide repeat. | 0.595 |
Mmc1_1445 | Mmc1_1448 | Mmc1_1445 | Mmc1_1448 | PFAM: protein of unknown function DUF107; KEGG: pfl:PFL_5949 hypothetical protein. | PFAM: Sporulation domain protein. | 0.578 |
Mmc1_1445 | mutS | Mmc1_1445 | Mmc1_1449 | PFAM: protein of unknown function DUF107; KEGG: pfl:PFL_5949 hypothetical protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.578 |
Mmc1_1447 | Mmc1_1445 | Mmc1_1447 | Mmc1_1445 | KEGG: rru:Rru_A2420 transferase hexapeptide repeat. | PFAM: protein of unknown function DUF107; KEGG: pfl:PFL_5949 hypothetical protein. | 0.595 |
Mmc1_1447 | Mmc1_1448 | Mmc1_1447 | Mmc1_1448 | KEGG: rru:Rru_A2420 transferase hexapeptide repeat. | PFAM: Sporulation domain protein. | 0.762 |
Mmc1_1447 | mutS | Mmc1_1447 | Mmc1_1449 | KEGG: rru:Rru_A2420 transferase hexapeptide repeat. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.762 |
Mmc1_1448 | Mmc1_1445 | Mmc1_1448 | Mmc1_1445 | PFAM: Sporulation domain protein. | PFAM: protein of unknown function DUF107; KEGG: pfl:PFL_5949 hypothetical protein. | 0.578 |
Mmc1_1448 | Mmc1_1447 | Mmc1_1448 | Mmc1_1447 | PFAM: Sporulation domain protein. | KEGG: rru:Rru_A2420 transferase hexapeptide repeat. | 0.762 |
Mmc1_1448 | mutS | Mmc1_1448 | Mmc1_1449 | PFAM: Sporulation domain protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.775 |
Mmc1_2541 | Mmc1_0002 | Mmc1_2541 | Mmc1_0002 | KEGG: pfo:Pfl_3001 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, Zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.684 |
Mmc1_2541 | mfd | Mmc1_2541 | Mmc1_1651 | KEGG: pfo:Pfl_3001 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, Zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.441 |
Mmc1_2541 | mutL | Mmc1_2541 | Mmc1_1040 | KEGG: pfo:Pfl_3001 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, Zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.466 |
Mmc1_2541 | mutS | Mmc1_2541 | Mmc1_1449 | KEGG: pfo:Pfl_3001 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, Zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.642 |