node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmc1_1884 | polA | Mmc1_1884 | Mmc1_3261 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.529 |
Mmc1_1884 | secA1 | Mmc1_1884 | Mmc1_3327 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.630 |
Mmc1_1884 | secA2 | Mmc1_1884 | Mmc1_2197 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.630 |
Mmc1_1884 | secA3 | Mmc1_1884 | Mmc1_2175 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.630 |
Mmc1_1884 | secY | Mmc1_1884 | Mmc1_0867 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.965 |
Mmc1_2174 | Mmc1_2176 | Mmc1_2174 | Mmc1_2176 | KEGG: nmu:Nmul_A0923 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: nmu:Nmul_A0925 peptidase, M50 family. | 0.931 |
Mmc1_2174 | Mmc1_2177 | Mmc1_2174 | Mmc1_2177 | KEGG: nmu:Nmul_A0923 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: sil:SPO2715 GAF domain protein. | 0.941 |
Mmc1_2174 | secA3 | Mmc1_2174 | Mmc1_2175 | KEGG: nmu:Nmul_A0923 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.813 |
Mmc1_2176 | Mmc1_2174 | Mmc1_2176 | Mmc1_2174 | KEGG: nmu:Nmul_A0925 peptidase, M50 family. | KEGG: nmu:Nmul_A0923 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.931 |
Mmc1_2176 | Mmc1_2177 | Mmc1_2176 | Mmc1_2177 | KEGG: nmu:Nmul_A0925 peptidase, M50 family. | KEGG: sil:SPO2715 GAF domain protein. | 0.949 |
Mmc1_2176 | secA2 | Mmc1_2176 | Mmc1_2197 | KEGG: nmu:Nmul_A0925 peptidase, M50 family. | SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.464 |
Mmc1_2176 | secA3 | Mmc1_2176 | Mmc1_2175 | KEGG: nmu:Nmul_A0925 peptidase, M50 family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.882 |
Mmc1_2177 | Mmc1_2174 | Mmc1_2177 | Mmc1_2174 | KEGG: sil:SPO2715 GAF domain protein. | KEGG: nmu:Nmul_A0923 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.941 |
Mmc1_2177 | Mmc1_2176 | Mmc1_2177 | Mmc1_2176 | KEGG: sil:SPO2715 GAF domain protein. | KEGG: nmu:Nmul_A0925 peptidase, M50 family. | 0.949 |
Mmc1_2177 | secA3 | Mmc1_2177 | Mmc1_2175 | KEGG: sil:SPO2715 GAF domain protein. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.852 |
der | secA1 | Mmc1_3587 | Mmc1_3327 | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.666 |
der | secA2 | Mmc1_3587 | Mmc1_2197 | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.705 |
der | secA3 | Mmc1_3587 | Mmc1_2175 | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.699 |
polA | Mmc1_1884 | Mmc1_3261 | Mmc1_1884 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.529 |
polA | secA1 | Mmc1_3261 | Mmc1_3327 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.737 |