STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddlATP-grasp enzyme, D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (384 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.980
AEV30960.1
UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.926
AEV30972.1
PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain.
  
 0.893
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.797
dinB
nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.784
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
 0.729
AEV28499.1
PFAM: Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; Belongs to the MurCDEF family.
 
  
 0.725
AEV28442.1
PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
 
  
 0.713
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.700
AEV28443.1
PFAM: Glycosyl transferase family 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase.
 
  
 0.675
Your Current Organism:
Sphaerochaeta pleomorpha
NCBI taxonomy Id: 158190
Other names: S. pleomorpha str. Grapes, Sphaerochaeta pleomorpha str. Grapes, Sphaerochaeta sp. Grapes, Spirochaeta sp. Grapes
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.