STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALI52973.1Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)    
Predicted Functional Partners:
spxA
ArsR family transcriptional regulator; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
 
 0.787
ALI51774.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.714
ALI53277.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.702
ALI52975.1
Adaptor protein; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family.
  
  
 0.684
ALI52972.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.635
nadK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.626
ALI52971.1
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.626
ALI51994.1
RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.623
ALI52073.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.539
ALI52345.1
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family.
   
   0.501
Your Current Organism:
Lactobacillus helveticus
NCBI taxonomy Id: 1587
Other names: ATCC 15009, Bacillus casei e, Bacillus e, CCUG 30139, CIP 103146, Caseobacterium e, DSM 20075, IFO 15019, L. helveticus, LMG 13555, LMG 22464 [[Lactobacillus suntoryeus]], LMG 6413, LMG:13555, LMG:22464 [[Lactobacillus suntoryeus]], LMG:6413, Lactobacillus helveticum, Lactobacillus sp. NCIM 2126, Lactobacillus sp. NCIM 2733, Lactobacillus suntoryeus, Lactobacillus suntoryeus Cachat and Priest 2005, Lactobacterium helveticum, NBRC 15019, NCIMB 14005 [[Lactobacillus suntoryeus]], NRRL B-4526, Plocamobacterium helveticum, Thermobacterium helveticum, strain SA [[Lactobacillus suntoryeus]]
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