node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Daro_1913 | panB | Daro_1913 | Daro_3185 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.938 |
Daro_1913 | panC | Daro_1913 | Daro_3186 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.938 |
Daro_1913 | panD | Daro_1913 | Daro_3187 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.464 |
Daro_2380 | panB | Daro_2380 | Daro_3185 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.760 |
Daro_2380 | panC | Daro_2380 | Daro_3186 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.506 |
Daro_3183 | Daro_3184 | Daro_3183 | Daro_3184 | 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Protein of unknown function DUF486. | 0.828 |
Daro_3183 | panB | Daro_3183 | Daro_3185 | 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.904 |
Daro_3183 | panC | Daro_3183 | Daro_3186 | 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.914 |
Daro_3183 | panD | Daro_3183 | Daro_3187 | 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.594 |
Daro_3183 | pcnB | Daro_3183 | Daro_3182 | 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Poly(A) polymerase, PcnB; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.956 |
Daro_3184 | Daro_3183 | Daro_3184 | Daro_3183 | Protein of unknown function DUF486. | 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | 0.828 |
Daro_3184 | panB | Daro_3184 | Daro_3185 | Protein of unknown function DUF486. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.825 |
Daro_3184 | panC | Daro_3184 | Daro_3186 | Protein of unknown function DUF486. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.844 |
Daro_3184 | panD | Daro_3184 | Daro_3187 | Protein of unknown function DUF486. | Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.555 |
Daro_3184 | pcnB | Daro_3184 | Daro_3182 | Protein of unknown function DUF486. | Poly(A) polymerase, PcnB; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.826 |
ilvD | ilvE | Daro_0302 | Daro_3294 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.973 |
ilvD | ilvE-2 | Daro_0302 | Daro_4078 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.973 |
ilvD | panB | Daro_0302 | Daro_3185 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.929 |
ilvE | ilvD | Daro_3294 | Daro_0302 | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.973 |
ilvE | ilvE-2 | Daro_3294 | Daro_4078 | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.902 |