STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD18231.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)    
Predicted Functional Partners:
KHD17323.1
Urocanate hydratase; Catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.984
hutI
Imidazolonepropionase; Catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.944
KHD21457.1
Peptidase M38; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.750
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.668
KHD19586.1
Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.662
KHD22368.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.649
KHD20477.1
Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
   
 
 0.558
KHD19711.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.557
KHD18217.1
Fatty acyl-AMP ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.557
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.528
Your Current Organism:
Paraburkholderia sacchari
NCBI taxonomy Id: 159450
Other names: Burkholderia sacchari, Burkholderia sacchari Bramer et al. 2001, CCT 6771, CCUG 46043, CIP 107211, DSM 17165, IPT 101, LMG 19450, LMG:19450, P. sacchari, Paraburkholderia sacchari (Braner et al. 2001) Sawana et al. 2015
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