node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PP_0747 | apt | PP_0747 | PP_4266 | Hypoxanthine-guanine phosphoribosyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.980 |
PP_0747 | gmk | PP_0747 | PP_5296 | Hypoxanthine-guanine phosphoribosyltransferase. | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.987 |
PP_0747 | guaA | PP_0747 | PP_1032 | Hypoxanthine-guanine phosphoribosyltransferase. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.952 |
PP_0747 | xpt | PP_0747 | PP_5265 | Hypoxanthine-guanine phosphoribosyltransferase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.987 |
PP_5295 | gmk | PP_5295 | PP_5296 | Homologs of previously reported genes of unknown function; Unknown function. | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.932 |
PP_5295 | rpoZ | PP_5295 | PP_5301 | Homologs of previously reported genes of unknown function; Unknown function. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.592 |
apt | PP_0747 | PP_4266 | PP_0747 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.980 |
apt | gmk | PP_4266 | PP_5296 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.952 |
apt | guaA | PP_4266 | PP_1032 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.987 |
apt | nrdA | PP_4266 | PP_1179 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.408 |
apt | xpt | PP_4266 | PP_5265 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.963 |
gmk | PP_0747 | PP_5296 | PP_0747 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.987 |
gmk | PP_5295 | PP_5296 | PP_5295 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Homologs of previously reported genes of unknown function; Unknown function. | 0.932 |
gmk | apt | PP_5296 | PP_4266 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.952 |
gmk | guaA | PP_5296 | PP_1032 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.976 |
gmk | ndk | PP_5296 | PP_0849 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.940 |
gmk | nrdA | PP_5296 | PP_1179 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.938 |
gmk | pyk | PP_5296 | PP_4301 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.933 |
gmk | pykA | PP_5296 | PP_1362 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family. | 0.932 |
gmk | rpoZ | PP_5296 | PP_5301 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.932 |