node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XF_0911 | rpoA | XF_0911 | XF_1176 | Stringent starvation protein A; Similar to SP|P05838 (percent identity: 46 %/query alignment coverage: 98.6 %/subject alignment coverage: 98.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the GST superfamily. | RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.902 |
XF_0911 | rpoB | XF_0911 | XF_2633 | Stringent starvation protein A; Similar to SP|P05838 (percent identity: 46 %/query alignment coverage: 98.6 %/subject alignment coverage: 98.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the GST superfamily. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.835 |
XF_0911 | rpoC | XF_0911 | XF_2632 | Stringent starvation protein A; Similar to SP|P05838 (percent identity: 46 %/query alignment coverage: 98.6 %/subject alignment coverage: 98.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the GST superfamily. | RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.909 |
XF_0911 | rpoD | XF_0911 | XF_1350 | Stringent starvation protein A; Similar to SP|P05838 (percent identity: 46 %/query alignment coverage: 98.6 %/subject alignment coverage: 98.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the GST superfamily. | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.897 |
XF_0911 | rpoZ | XF_0911 | XF_1502 | Stringent starvation protein A; Similar to SP|P05838 (percent identity: 46 %/query alignment coverage: 98.6 %/subject alignment coverage: 98.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the GST superfamily. | RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.854 |
XF_1540 | rpoA | XF_1540 | XF_1176 | Transcriptional regulator (Crp/Fnr family); Similar to SP|P22260 (percent identity: 85 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 210. | RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.925 |
XF_1540 | rpoB | XF_1540 | XF_2633 | Transcriptional regulator (Crp/Fnr family); Similar to SP|P22260 (percent identity: 85 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 210. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.901 |
XF_1540 | rpoC | XF_1540 | XF_2632 | Transcriptional regulator (Crp/Fnr family); Similar to SP|P22260 (percent identity: 85 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 210. | RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.882 |
XF_1540 | rpoD | XF_1540 | XF_1350 | Transcriptional regulator (Crp/Fnr family); Similar to SP|P22260 (percent identity: 85 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 210. | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.936 |
XF_1540 | rpoZ | XF_1540 | XF_1502 | Transcriptional regulator (Crp/Fnr family); Similar to SP|P22260 (percent identity: 85 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 210. | RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.837 |
dnaK | gyrB | XF_2340 | XF_0005 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.853 |
dnaK | lepA | XF_2340 | XF_2243 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.596 |
dnaK | rpoA | XF_2340 | XF_1176 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.541 |
dnaK | rpoB | XF_2340 | XF_2633 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.532 |
dnaK | rpoD | XF_2340 | XF_1350 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.852 |
gyrB | dnaK | XF_0005 | XF_2340 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.853 |
gyrB | lepA | XF_0005 | XF_2243 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.668 |
gyrB | rpoB | XF_0005 | XF_2633 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.799 |
gyrB | rpoC | XF_0005 | XF_2632 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.471 |
gyrB | rpoD | XF_0005 | XF_1350 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.832 |