node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XF_0259 | murJ | XF_0259 | XF_2420 | Phosphomannose isomerase-GDP-mannose pyrophosphorylase; Similar to SP|P29956 (percent identity: 84 %/query alignment coverage: 96.9 %/subject alignment coverage: 100.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the mannose-6-phosphate isomerase type 2 family. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.563 |
XF_1272 | murJ | XF_1272 | XF_2420 | Conserved hypothetical protein; Similar to SP|Q50606 (percent identity: 30 %/query alignment coverage: 52.1 %/subject alignment coverage: 85.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.667 |
XF_2419 | ileS | XF_2419 | XF_2418 | Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.862 |
XF_2419 | lspA | XF_2419 | XF_2417 | Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.675 |
XF_2419 | murJ | XF_2419 | XF_2420 | Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.873 |
XF_2419 | rpsT | XF_2419 | XF_2421 | Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.475 |
ftsW | murA | XF_0796 | XF_1415 | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.747 |
ftsW | murF | XF_0796 | XF_0794 | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.979 |
ftsW | murJ | XF_0796 | XF_2420 | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.646 |
ileS | XF_2419 | XF_2418 | XF_2419 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family. | 0.862 |
ileS | lspA | XF_2418 | XF_2417 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.805 |
ileS | murJ | XF_2418 | XF_2420 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.636 |
ileS | rpsT | XF_2418 | XF_2421 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.452 |
lspA | XF_2419 | XF_2417 | XF_2419 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family. | 0.675 |
lspA | ileS | XF_2417 | XF_2418 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.805 |
lspA | murJ | XF_2417 | XF_2420 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.540 |
murA | ftsW | XF_1415 | XF_0796 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.747 |
murA | murF | XF_1415 | XF_0794 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.804 |
murA | murJ | XF_1415 | XF_2420 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.538 |
murF | ftsW | XF_0794 | XF_0796 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.979 |