STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEConserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (212 aa)    
Predicted Functional Partners:
coaD
Lipopolysaccharide synthesis enzyme; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
    
 0.935
XF_2537
Pre-pilin leader peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
    0.911
XF_0186
Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
    
  0.904
XF_1934
HetI protein; Similar to SP|P37695 (percent identity: 35 %/query alignment coverage: 93.4 %/subject alignment coverage: 77.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the P-Pant transferase superfamily.
     
 0.901
XF_2538
Fimbrial assembly protein; Similar to SP|P22609 (percent identity: 56 %/query alignment coverage: 81.4 %/subject alignment coverage: 98.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.803
mutM1
Formamidopyrimidine DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
  
  
 0.589
XF_0170
Formamidopyrimidine DNA glycosylase; Similar to SP|P05523 (percent identity: 51 %/query alignment coverage: 99.6 %/subject alignment coverage: 100.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.589
XF_2539
Fimbrial protein; Similar to GI|1073087 (percent identity: 48 %/query alignment coverage: 100.0 %/subject alignment coverage: 108.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
     0.575
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.529
pheT
phenylalanyl-tRNA sinthetase beta chain; Similar to SP|P07395 (percent identity: 42 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
   
 0.520
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.