STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
XF_1073
Succinate dehydrogenase iron-sulfur protein; Similar to SP|Q59662 (percent identity: 70 %/query alignment coverage: 99.2 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.983
XF_1072
Succinate dehydrogenase, flavoprotein subunit; Similar to SP|P31038 (percent identity: 69 %/query alignment coverage: 99.7 %/subject alignment coverage: 99.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.982
XF_1070
Succinate dehydrogenase, membrane anchor subunit; Similar to GI|3169722 (percent identity: 38 %/query alignment coverage: 88.7 %/subject alignment coverage: 95.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.977
XF_1549
Dihydrolipoamide S-succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
 0.963
XF_1071
Succinate dehydrogenase, membrane anchor subunit; Similar to GI|3169723 (percent identity: 36 %/query alignment coverage: 96.1 %/subject alignment coverage: 91.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.943
XF_1550
Oxoglutarate dehydrogenase; Similar to SP|Q59106 (percent identity: 54 %/query alignment coverage: 97.6 %/subject alignment coverage: 99.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.931
XF_0869
Dihydrolipoamide acetyltranferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.926
prpB
Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.917
XF_0868
Dihydrolipoamide dehydrogenase; Similar to GI|1073212 (percent identity: 57 %/query alignment coverage: 100.2 %/subject alignment coverage: 101.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.876
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.