node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEM61047.1 | CEM61048.1 | TPHV1_130085 | TPHV1_130086 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | 0.448 |
CEM61047.1 | CEM61478.1 | TPHV1_130085 | TPHV1_20015 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pyridine nucleotide-disulfide oxidoreductase (modular protein). | 0.505 |
CEM61047.1 | CEM61787.1 | TPHV1_130085 | TPHV1_210020 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.559 |
CEM61047.1 | CEM62891.1 | TPHV1_130085 | TPHV1_50151 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Inosine 5-monophosphate dehydrogenase. | 0.496 |
CEM61047.1 | hslO | TPHV1_130085 | TPHV1_100006 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Chaperonin HslO. | 0.465 |
CEM61047.1 | polA | TPHV1_130085 | TPHV1_80113 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.559 |
CEM61047.1 | proS | TPHV1_130085 | TPHV1_90080 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.451 |
CEM61047.1 | trmB | TPHV1_130085 | TPHV1_40139 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.476 |
CEM61047.1 | trmD | TPHV1_130085 | TPHV1_50010 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.432 |
CEM61047.1 | truA | TPHV1_130085 | TPHV1_240025 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.480 |
CEM61048.1 | CEM61047.1 | TPHV1_130086 | TPHV1_130085 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.448 |
CEM61478.1 | CEM61047.1 | TPHV1_20015 | TPHV1_130085 | Pyridine nucleotide-disulfide oxidoreductase (modular protein). | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.505 |
CEM61478.1 | CEM62891.1 | TPHV1_20015 | TPHV1_50151 | Pyridine nucleotide-disulfide oxidoreductase (modular protein). | Inosine 5-monophosphate dehydrogenase. | 0.734 |
CEM61478.1 | polA | TPHV1_20015 | TPHV1_80113 | Pyridine nucleotide-disulfide oxidoreductase (modular protein). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.471 |
CEM61478.1 | trmD | TPHV1_20015 | TPHV1_50010 | Pyridine nucleotide-disulfide oxidoreductase (modular protein). | tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.466 |
CEM61478.1 | truA | TPHV1_20015 | TPHV1_240025 | Pyridine nucleotide-disulfide oxidoreductase (modular protein). | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.670 |
CEM61787.1 | CEM61047.1 | TPHV1_210020 | TPHV1_130085 | NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.559 |
CEM61787.1 | trmB | TPHV1_210020 | TPHV1_40139 | NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.626 |
CEM61787.1 | truA | TPHV1_210020 | TPHV1_240025 | NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.434 |
CEM62891.1 | CEM61047.1 | TPHV1_50151 | TPHV1_130085 | Inosine 5-monophosphate dehydrogenase. | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.496 |