STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AN8275.2Citrate synthase, mitochondrial precursor (Eurofung) (474 aa)    
Predicted Functional Partners:
AN6717.2
Malate dehydrogenase (Eurofung)
  
 0.994
AN5525.2
Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle. Also catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis
  
 0.988
AN6499.2
Malate dehydrogenase, NAD-dependent (AFU_orthologue; AFUA_6G05210); Belongs to the LDH/MDH superfamily
  
 0.987
AN4462.2
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
  
 0.986
AN6653.2
Malate synthase, glyoxysomal; Malate Synthase (Eurofung)
  
 
 0.985
AN6708.2
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
  
 0.983
AN8707.2
Fumarate hydratase, putative (AFU_orthologue; AFUA_6G02470)
  
 0.981
AN5300.2
Aconitate hydratase, putative (Eurofung); Belongs to the aconitase/IPM isomerase family
  
 0.976
AN2436.2
ATP citrate lyase, subunit 1, putative (AFU_orthologue; AFUA_6G10650)
  
 0.956
AN5031.2
Conserved hypothetical protein: similar to cytplasmic malate dehydrogenase (Eurofung); Belongs to the LDH/MDH superfamily
  
 0.955
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 162425
Other names: A. nidulans, ATCC 10074, Aspergillus nidulans, Aspergillus nidulellus, Emericella nidulans
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