STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KJS21211.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)    
Predicted Functional Partners:
KJS20765.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
KJS20220.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
sdhB
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
KJS21067.1
NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.961
KJS22625.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.887
KJS20821.1
Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.873
KJS20043.1
NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.871
nuoD
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
   
 0.870
KJS19968.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.797
KJS19750.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.790
Your Current Organism:
Clostridiaceae bacterium BRHc20a
NCBI taxonomy Id: 1629719
Other names: C. bacterium BRH_c20a, Clostridiaceae bacterium BRH_c20a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.