STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serSSeryl-trna synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec) (425 aa)    
Predicted Functional Partners:
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis
   
 
 0.968
argS
Arginyl-trna synthetase; Arginine--tRNA ligase; Identified by similarity to EGAD:30453; match to TIGR00456 protein family HMM TIGR00456; match to PF00750 protein family HMM PF00750; match to PF05746 protein family HMM PF05746; match to PF03485 protein family HMM PF03485
  
 
 0.932
cysS
Cysteinyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family
 
 
 0.898
groEL
Chaperonin, 60 kda; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
  
 
 0.885
thrS
Threonyl-trna synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)
 
 
 0.882
rplL
Large subunit ribosomal protein l7/l12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
   
  
 0.865
petA
Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
  
  
 0.865
hisS
Histidyl-trna synthetase; Histidine--tRNA ligase; Identified by similarity to SP:P04804; match to TIGR00442 protein family HMM TIGR00442; match to PF00587 protein family HMM PF00587; match to PF03129 protein family HMM PF03129
 
 
 0.826
trpS
Tryptophanyl-trna synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp)
  
 
 0.816
pheT
Phenylalanyl-trna synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
 
  
 0.813
Your Current Organism:
Wolbachia sp. Dme
NCBI taxonomy Id: 163164
Other names: W. endosymbiont of Drosophila melanogaster, Wolbachia (endosymbiont of Drosophila melanogaster), Wolbachia endosymbiont of Drosophila melanogaster, Wolbachia pipientis wMel, Wolbachia sp. wMel
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