STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recJPutative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB. increased sensitivity to DNA-damanging agents. However, cells lacking RecJ and with a mutated AadAB enzyme were extremely sensitive to these agents, as sensitive as recA deletion strains. The doubly mutated strain shows 10-fold impaired growth in the absence of these agents; sp|O32044|RECJ_BACSU;evalue=3e-095; PctID=35.50; score=349. (571 aa)    
Predicted Functional Partners:
recQ3
ATP-dependent DNA helicase RecQ; Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase. ProRule:PRU00328}. Sequence=AAA24517.1; Type=Erroneous initiation; Evidence=; Sequence=AAA67618.1; Type=Erroneous initiation; Evidence=; sp|P15043|RECQ_ECOLI;evalue=2e-076; PctID=44.48; score=287.
    
 0.974
priA
Primosomal protein N' {ECO:0000255|HAMAP-Rule:MF_00983}; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.683
mutS-2
DNA mismatch repair protein MutS {ECO:0000255|HAMAP-Rule:MF_00096}; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
  
 0.653
ssb
Single-stranded DNA-binding protein {ECO:0000255|HAMAP-Rule:MF_00984}; sp|Q8A7M7|SSB_BACTN;evalue=2e-041; PctID=66.39; score=167.
 
 
 0.576
recQ1
DNA helicase. ProRule:PRU00328}; sp|P71359|RECQ_HAEIN;evalue=4e-106; PctID=36.69; score=386.
    
 0.573
mutL
DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.534
pheT-3
Phenylalanine-tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00283}; sp|Q64T65|SYFB_BACFR;evalue=0.0; PctID=59.93; score=988; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.503
pheT
Phenylalanine-tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00283}; sp|Q5LC76|SYFB_BACFN, sp|Q64T65|SYFB_BACFR;evalue=3e-169; PctID=67.82; score=595; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
    0.495
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
   
 0.493
gntX
Protein GntX; Could be involved in gluconate metabolism. Sequence=AAA58211.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Evidence=; sp|P46846|GNTX_ECOLI;evalue=4e-016; PctID=29.49; score=85.1.
 
     0.487
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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