STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbpAElectron transporter; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. (117 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.997
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.996
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.994
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.993
sigA
RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.992
AHU88760.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.862
AHU88827.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.775
AHU88853.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.765
AHU88797.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.763
AHU88826.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.750
Your Current Organism:
Trueperella pyogenes
NCBI taxonomy Id: 1661
Other names: ATCC 19411, Actinomyces pyogenes, Arcanibacterium pyogenes, Arcanobacterium pyogenes, Bacillus pyogenes, CCUG 13230, CIP 103129, Corynebacterium pyogenes, DSM 20630, LMG 16162, LMG:16162, NCTC 5224, T. pyogenes, strain C-100
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