STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvKBranched-chain-amino-acid aminotransferase 2. (354 aa)    
Predicted Functional Partners:
ilvD_2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 0.985
ilvD_1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.983
leuA_2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.982
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.928
mccB
Cystathionine gamma-lyase.
   
 0.920
tdcB
L-threonine dehydratase catabolic TdcB.
  
 
 0.912
hom
Homoserine dehydrogenase.
  
 
 0.889
porC
Pyruvate synthase subunit porC.
  
 
 0.868
porB
Pyruvate synthase subunit porB.
  
 
 0.867
serB
Phosphoserine phosphatase.
    
 0.846
Your Current Organism:
Roseburia intestinalis
NCBI taxonomy Id: 166486
Other names: DSM 14610, NCIMB 13810, R. intestinalis, Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006, strain L1-82
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