STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALV63131.1Ribokinase, putative; Belongs to the carbohydrate kinase PfkB family. (316 aa)    
Predicted Functional Partners:
ALV61846.1
Uncharacterized protein.
 
  
 0.595
ALV63129.1
TldE protein, part of TldE/TldD proteolytic complex.
       0.566
ALV63130.1
TldD protein, part of TldE/TldD proteolytic complex.
   
   0.561
ALV63214.1
Adenine phosphoribosyltransferase, fused to N-terminal DNA-binding domain.
 
 
 0.560
ALV62134.1
Sugar phosphate isomerase/epimerase.
  
  
 0.542
ALV63881.1
Putative oxidoreductase, related to GH109 family.
  
  
 0.516
ALV63685.1
NAD(P)(+)-dependent non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.507
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.489
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.471
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.468
Your Current Organism:
Thermococcus sp. 2319x1
NCBI taxonomy Id: 1674923
Other names: T. sp. 2319x1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.