node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddlA | ftsQ | Pro_1380 | Pro_1382 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Cell division protein FtsQ; Essential cell division protein. | 0.937 |
ddlA | murB | Pro_1380 | Pro_0021 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.935 |
ddlA | murC | Pro_1380 | Pro_0022 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.964 |
ddlA | murD | Pro_1380 | Pro_1439 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.794 |
ddlA | murE | Pro_1380 | Pro_0412 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.702 |
ddlA | murF | Pro_1380 | Pro_1051 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
ddlA | murG | Pro_1380 | Pro_0223 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.850 |
ddlA | murI | Pro_1380 | Pro_1043 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.473 |
ddlA | rfe-2 | Pro_1380 | Pro_1878 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.612 |
ftsQ | ddlA | Pro_1382 | Pro_1380 | Cell division protein FtsQ; Essential cell division protein. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.937 |
ftsQ | murB | Pro_1382 | Pro_0021 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.631 |
ftsQ | murC | Pro_1382 | Pro_0022 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.876 |
ftsQ | murD | Pro_1382 | Pro_1439 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.884 |
ftsQ | murE | Pro_1382 | Pro_0412 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.613 |
ftsQ | murF | Pro_1382 | Pro_1051 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.728 |
ftsQ | murG | Pro_1382 | Pro_0223 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.903 |
murB | ddlA | Pro_0021 | Pro_1380 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.935 |
murB | ftsQ | Pro_0021 | Pro_1382 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | Cell division protein FtsQ; Essential cell division protein. | 0.631 |
murB | murC | Pro_0021 | Pro_0022 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
murB | murD | Pro_0021 | Pro_1439 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.802 |