node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pro_0127 | guaA | Pro_0127 | Pro_0038 | 6-pyruvoyl-tetrahydropterin synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.427 |
Pro_0127 | nrdG | Pro_0127 | Pro_1854 | 6-pyruvoyl-tetrahydropterin synthase. | Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.972 |
Pro_0127 | queC | Pro_0127 | Pro_1855 | 6-pyruvoyl-tetrahydropterin synthase. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.813 |
Pro_0127 | queF | Pro_0127 | Pro_1614 | 6-pyruvoyl-tetrahydropterin synthase. | GTP cyclohydrolase I family enzyme; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.651 |
Pro_0583 | guaA | Pro_0583 | Pro_0038 | 6-pyruvoyl-tetrahydropterin synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.427 |
Pro_0583 | nrdG | Pro_0583 | Pro_1854 | 6-pyruvoyl-tetrahydropterin synthase. | Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.704 |
Pro_0583 | queC | Pro_0583 | Pro_1855 | 6-pyruvoyl-tetrahydropterin synthase. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.813 |
Pro_0583 | queF | Pro_0583 | Pro_1614 | 6-pyruvoyl-tetrahydropterin synthase. | GTP cyclohydrolase I family enzyme; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.699 |
Pro_1857 | aspS | Pro_1857 | Pro_1852 | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.561 |
Pro_1857 | gcvT-2 | Pro_1857 | Pro_1851 | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.522 |
Pro_1857 | nrdG | Pro_1857 | Pro_1854 | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.679 |
Pro_1857 | pyrG | Pro_1857 | Pro_1853 | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.684 |
Pro_1857 | queC | Pro_1857 | Pro_1855 | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.822 |
Pro_1857 | trpE-2 | Pro_1857 | Pro_1856 | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | Anthranilate/para-aminobenzoate synthase component I. | 0.890 |
aspS | Pro_1857 | Pro_1852 | Pro_1857 | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 4-amino-4-deoxychorismate lyase related type IV aminotransferase. | 0.561 |
aspS | gcvT-2 | Pro_1852 | Pro_1851 | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.677 |
aspS | guaA | Pro_1852 | Pro_0038 | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.787 |
aspS | nrdG | Pro_1852 | Pro_1854 | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.630 |
aspS | pyrG | Pro_1852 | Pro_1853 | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.830 |
aspS | queC | Pro_1852 | Pro_1855 | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.551 |