STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqoPutative malate/quinone oxidoreductase; COG579 Predicted dehydrogenase [General function prediction only]. (497 aa)    
Predicted Functional Partners:
gltA
COG372 Citrate synthase [Energy production and conversion]; Belongs to the citrate synthase family.
  
 
 0.957
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.937
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.935
aspC
Aminotransferases class-I; COG436 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism].
   
 
 0.833
argH
Fumarate lyase:Delta crystallin; COG165 Argininosuccinate lyase [Amino acid transport and metabolism].
    
 0.820
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
 
  0.814
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
  0.800
purB
Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.800
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.696
ABM71688.1
COG694 Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones].
       0.663
Your Current Organism:
Prochlorococcus marinus MIT9515
NCBI taxonomy Id: 167542
Other names: P. marinus str. MIT 9515, Prochlorococcus marinus str. MIT 9515
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