node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPS_0423 | CPS_3233 | CPS_0423 | CPS_3233 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Conserved hypothetical protein; Identified by similarity to GP:28805913. | 0.911 |
CPS_0423 | cdd | CPS_0423 | CPS_1969 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.901 |
CPS_0423 | deoA | CPS_0423 | CPS_1970 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.902 |
CPS_0423 | deoD | CPS_0423 | CPS_1978 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Purine nucleoside phosphorylase; Identified by similarity to SP:P09743; match to protein family HMM PF01048; match to protein family HMM TIGR00107. | 0.903 |
CPS_0423 | ppnP | CPS_0423 | CPS_4838 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.913 |
CPS_0423 | surE | CPS_0423 | CPS_1075 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.911 |
CPS_0423 | tdk | CPS_0423 | CPS_1971 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Thymidine kinase; Identified by similarity to SP:P23331; match to protein family HMM PF00265. | 0.902 |
CPS_0423 | thyA | CPS_0423 | CPS_3621 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.904 |
CPS_0423 | tmk | CPS_0423 | CPS_2302 | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.902 |
CPS_3233 | CPS_0423 | CPS_3233 | CPS_0423 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 0.911 |
CPS_3233 | cdd | CPS_3233 | CPS_1969 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.901 |
CPS_3233 | deoA | CPS_3233 | CPS_1970 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.900 |
CPS_3233 | deoD | CPS_3233 | CPS_1978 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Purine nucleoside phosphorylase; Identified by similarity to SP:P09743; match to protein family HMM PF01048; match to protein family HMM TIGR00107. | 0.908 |
CPS_3233 | ppnP | CPS_3233 | CPS_4838 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
CPS_3233 | surE | CPS_3233 | CPS_1075 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
CPS_3233 | tdk | CPS_3233 | CPS_1971 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Thymidine kinase; Identified by similarity to SP:P23331; match to protein family HMM PF00265. | 0.901 |
CPS_3233 | thyA | CPS_3233 | CPS_3621 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
CPS_3233 | tmk | CPS_3233 | CPS_2302 | Conserved hypothetical protein; Identified by similarity to GP:28805913. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.904 |
cdd | CPS_0423 | CPS_1969 | CPS_0423 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 0.901 |
cdd | CPS_3233 | CPS_1969 | CPS_3233 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Conserved hypothetical protein; Identified by similarity to GP:28805913. | 0.901 |