STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iccCyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (263 aa)    
Predicted Functional Partners:
CPS_0423
HAD-superfamily hydrolase, subfamily IA, variant 3 family protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509.
 
  
  0.923
CPS_4114
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
  
  
  0.914
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
  0.902
CPS_3537
Identified by match to protein family HMM PF03641.
    
  0.901
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.901
surE
Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
purB
Adenylosuccinate lyase; Identified by similarity to SP:P25739; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
CPS_3337
Putative adenylate cyclase; Identified by similarity to SP:Q9Z3Q0.
     
  0.900
CPS_4177
Conserved hypothetical protein; Identified by similarity to OMNI:SO3900; match to protein family HMM PF05728.
  
 0.829
nudF
ADP-ribose pyrophosphatase; Identified by similarity to SP:P36651; match to protein family HMM PF00293; match to protein family HMM TIGR00052.
    
 0.727
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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