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trpA protein (Bifidobacterium adolescentis) - STRING interaction network
"trpA" - Tryptophan synthase alpha chain in Bifidobacterium adolescentis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (291 aa)    
Predicted Functional Partners:
trpB
Multifunctional fusion protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family (697 aa)
  0.999
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (518 aa)
 
 
  0.992
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (351 aa)
   
  0.989
pabA
annotation not available (214 aa)
 
   
  0.979
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (435 aa)
     
 
  0.922
BADO_0502
annotation not available (336 aa)
   
 
  0.915
BADO_1676
annotation not available (421 aa)
     
 
  0.914
serB
annotation not available (227 aa)
   
 
  0.904
BADO_0694
annotation not available (486 aa)
         
  0.901
metAA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine; Belongs to the MetA family (344 aa)
         
  0.807
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 1680
Other names: AS 1.2190, ATCC 15703, B. adolescentis, BCRC 14606, Bifidobacterium adolescentis, CCRC 14606, CCUG 17359, CCUG 18363, CIP 64.59, DSM 20083, LMG 10502, NCAIM B.01822, NCTC 11814
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