Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
annotation not available (421 aa)
Predicted Functional Partners:
annotation not available (246 aa)
annotation not available (282 aa)
annotation not available (197 aa)
tRNA (adenine(58)-N(1))-methyltransferase TrmI; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA (351 aa)
annotation not available (824 aa)
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (520 aa)
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (899 aa)
annotation not available (869 aa)
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (308 aa)