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msrA-2 protein (Streptococcus pneumoniae TIGR4) - STRING interaction network
"msrA-2" - Peptide methionine sulfoxide reductase MsrA/MsrB 1 in Streptococcus pneumoniae TIGR4
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
msrA-2Peptide methionine sulfoxide reductase MsrA/MsrB 1; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (312 aa)    
Predicted Functional Partners:
SP_0659
Thioredoxin family protein; Identified by similarity to EGAD-28452 (188 aa)
 
  0.901
SP_0313
Glutathione peroxidase; Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family (158 aa)
   
 
  0.813
gap
Glyceraldehyde-3-phosphate dehydrogenase; Identified by similarity to EGAD-102441; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family (335 aa)
     
 
  0.797
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (520 aa)
   
   
  0.777
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (492 aa)
         
  0.768
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (366 aa)
         
  0.766
sodA
Superoxide dismutase [Mn]; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. May play a critical role against oxidative stress, affecting both the survival and the virulence of S.pneumoniae (201 aa)
   
   
  0.757
SP_1161
Dihydrolipoyl dehydrogenase; Identified by similarity to EGAD-13144; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350 (567 aa)
   
 
  0.747
msrA-1
Peptide methionine sulfoxide reductase MsrA/MsrB 2; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) (311 aa)
 
 
0.746
trx
Thioredoxin; Identified by similarity to EGAD-45993; match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family (104 aa)
   
   
  0.734
Your Current Organism:
Streptococcus pneumoniae TIGR4
NCBI taxonomy Id: 170187
Other names: S. pneumoniae TIGR4, Streptococcus pneumoniae TIGR4
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