STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP52127.1Isocitrate lyase. (436 aa)    
Predicted Functional Partners:
AOP52129.1
Malate synthase.
 
 0.993
AOP54221.1
Malate synthase; Belongs to the malate synthase family.
 
 0.992
AOP52126.1
Transcriptional regulator, XRE family.
 
   
 0.835
AOP52428.1
Aconitate hydratase.
  
 
 0.620
AOP54010.1
Aconitate hydratase - 2-methylisocitrate dehydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.620
AOP54558.1
Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.599
AOP52182.1
Succinate dehydrogenase flavoprotein subunit.
   
 
 0.595
AOP54557.1
Succinate dehydrogenase flavoprotein subunit.
   
 
 0.595
AOP54556.1
Succinate dehydrogenase hydrophobic membrane anchor protein.
   
 
 0.586
AOP53094.1
Ribonuclease E inhibitor RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
 
    0.575
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.