STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OES44738.14-oxalocrotonate tautomerase; 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (65 aa)    
Predicted Functional Partners:
OES44739.1
4-oxalocrotonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.945
OES44742.1
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.909
OES44740.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
   
 0.868
OES44741.1
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.846
OES44737.1
Extradiol ring-cleavage dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.783
OES45033.1
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.748
OES46094.1
Ring-cleaving dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.719
OES44744.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.489
OES46681.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.479
OES45078.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
     0.458
Your Current Organism:
Domibacillus iocasae
NCBI taxonomy Id: 1714016
Other names: CCTCC AB 2015183, D. iocasae, DSM 29979, Domibacillus iocasae Sun and Sun 2016, Domibacillus sp. S6, strain S6
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