STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (322 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Identified by similarity to EGAD:37614; match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
 
 
 0.997
pgi
Glucose-6-phosphate isomerase; Identified by similarity to EGAD:10310; match to protein family HMM PF00342.
  
 0.982
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.971
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.960
fdaB
Fructose-bisphosphate aldolase, class I; Identified by similarity to SP:Q07159; match to protein family HMM PF00274; Belongs to the class I fructose-bisphosphate aldolase family.
  
 0.938
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.931
tal
Transaldolase; Identified by match to protein family HMM PF00923.
  
 
 0.928
SERP0217
SIS domain protein; Identified by match to protein family HMM PF01380.
    
 0.923
fbp
Fructose-1,6-bisphosphatase, putative; Identified by similarity to EGAD:37656.
     
 0.922
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by similarity to EGAD:16117; match to protein family HMM PF02502; match to protein family HMM TIGR00689.
  
 
 0.919
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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