STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacRLactose phosphotransferase system repressor; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer (By similarity). (251 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose-specific IIABC components; Identified by similarity to GP:9501781; match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
 
  
 0.947
lacC
Tagatose-6-phosphate kinase; Identified by similarity to EGAD:6991; match to protein family HMM PF00294; match to protein family HMM TIGR01231; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.935
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by similarity to EGAD:16117; match to protein family HMM PF02502; match to protein family HMM TIGR00689.
 
  
 0.878
lacA
Galactose-6-phosphate isomerase, LacA subunit; Identified by similarity to EGAD:13018; match to protein family HMM PF02502; match to protein family HMM TIGR00689.
 
  
 0.873
fruK
1-phosphofructokinase; Identified by similarity to EGAD:107874; match to protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.826
SERP2260
PTS system, fructose-specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
 
  
 0.790
SERP0516
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.767
lacE
PTS system, lactose-specific IIBC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport.
 
  
 0.745
lacD
Tagatose 1,6-diphosphate aldolase; Identified by similarity to EGAD:9829; match to protein family HMM PF04274; match to protein family HMM TIGR01232; Belongs to the aldolase LacD family.
 
   
 0.732
lacF
PTS system, lactose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport.
 
   
 0.599
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.