STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase, putative; Identified by similarity to EGAD:37656. (654 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Identified by similarity to EGAD:10310; match to protein family HMM PF00342.
     
 0.948
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
  
 0.926
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.922
fruK
1-phosphofructokinase; Identified by similarity to EGAD:107874; match to protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
    
 0.909
SERP1494
Fructokinase, putative; Identified by match to protein family HMM PF00294.
    
 0.906
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
 0.903
tal
Transaldolase; Identified by match to protein family HMM PF00923.
     
 0.902
manA-1
Mannose-6-phosphate isomerase, class I; Identified by similarity to EGAD:14340; match to protein family HMM PF01238; match to protein family HMM TIGR00218; Belongs to the mannose-6-phosphate isomerase type 1 family.
     
 0.901
manA-2
Mannose-6-phosphate isomerase, class I; Identified by similarity to EGAD:14340; match to protein family HMM PF01238; match to protein family HMM TIGR00218; Belongs to the mannose-6-phosphate isomerase type 1 family.
     
 0.901
SERP0217
SIS domain protein; Identified by match to protein family HMM PF01380.
     
  0.900
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.