Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP0241 | icaC | SERP0241 | SERP2296 | Conserved hypothetical protein; Identified by similarity to OMNI:SA0639; Belongs to the UPF0741 family. | Intercellular adhesion protein C; Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane (By similarity). Is essential for long-chain PIA synthesis. | 0.499 |
| aap | atlE | SERP2398 | SERP0636 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | 0.755 |
| aap | bhp | SERP2398 | SERP2392 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Cell wall associated biofilm protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF00801; match to protein family HMM PF04650; match to protein family HMM PF05345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | 0.482 |
| aap | icaA | SERP2398 | SERP2293 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | 0.755 |
| aap | icaB | SERP2398 | SERP2295 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion protein B; Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. In fact, the IcaB deacetylase converts 15 to 20% of the GlcNAc residues of PNAG to glucosamine. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions. Deacetylation of the polymer is also essential for key virulence mechanisms of S.epidermidis, namely biof [...] | 0.755 |
| aap | icaC | SERP2398 | SERP2296 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion protein C; Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane (By similarity). Is essential for long-chain PIA synthesis. | 0.755 |
| aap | icaD | SERP2398 | SERP2294 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion protein D; Necessary for the synthesis of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Is required for full IcaA N- acetylglucosaminyltransferase activity. | 0.755 |
| aap | icaR | SERP2398 | SERP2292 | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | 0.755 |
| atlE | aap | SERP0636 | SERP2398 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | 0.755 |
| atlE | bhp | SERP0636 | SERP2392 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Cell wall associated biofilm protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF00801; match to protein family HMM PF04650; match to protein family HMM PF05345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | 0.765 |
| atlE | ebpS | SERP0636 | SERP1048 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Elastin binding protein, putative; Identified by match to protein family HMM PF01476. | 0.771 |
| atlE | icaA | SERP0636 | SERP2293 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | 0.837 |
| atlE | icaB | SERP0636 | SERP2295 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Intercellular adhesion protein B; Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. In fact, the IcaB deacetylase converts 15 to 20% of the GlcNAc residues of PNAG to glucosamine. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions. Deacetylation of the polymer is also essential for key virulence mechanisms of S.epidermidis, namely biof [...] | 0.774 |
| atlE | icaC | SERP0636 | SERP2296 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Intercellular adhesion protein C; Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane (By similarity). Is essential for long-chain PIA synthesis. | 0.755 |
| atlE | icaD | SERP0636 | SERP2294 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Intercellular adhesion protein D; Necessary for the synthesis of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Is required for full IcaA N- acetylglucosaminyltransferase activity. | 0.687 |
| atlE | icaR | SERP0636 | SERP2292 | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | 0.785 |
| bhp | aap | SERP2392 | SERP2398 | Cell wall associated biofilm protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF00801; match to protein family HMM PF04650; match to protein family HMM PF05345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Accumulation associated protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | 0.482 |
| bhp | atlE | SERP2392 | SERP0636 | Cell wall associated biofilm protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF00801; match to protein family HMM PF04650; match to protein family HMM PF05345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family. | 0.765 |
| bhp | icaA | SERP2392 | SERP2293 | Cell wall associated biofilm protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF00801; match to protein family HMM PF04650; match to protein family HMM PF05345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | 0.790 |
| bhp | icaB | SERP2392 | SERP2295 | Cell wall associated biofilm protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF00801; match to protein family HMM PF04650; match to protein family HMM PF05345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. | Intercellular adhesion protein B; Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. In fact, the IcaB deacetylase converts 15 to 20% of the GlcNAc residues of PNAG to glucosamine. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions. Deacetylation of the polymer is also essential for key virulence mechanisms of S.epidermidis, namely biof [...] | 0.623 |
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