node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SERP0389 | SERP0856 | SERP0389 | SERP0856 | Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.956 |
SERP0389 | nrdD | SERP0389 | SERP2183 | Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Anaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF01228. | 0.456 |
SERP0389 | pflA | SERP0389 | SERP2365 | Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.802 |
SERP0389 | pflB | SERP0389 | SERP2366 | Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.971 |
SERP0516 | lacR | SERP0516 | SERP1796 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Lactose phosphotransferase system repressor; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer (By similarity). | 0.767 |
SERP0516 | pflA | SERP0516 | SERP2365 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.607 |
SERP0516 | pflB | SERP0516 | SERP2366 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.580 |
SERP0856 | SERP0389 | SERP0856 | SERP0389 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.956 |
SERP0856 | pdhA | SERP0856 | SERP0680 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Pyruvate dehydrogenase complex E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.932 |
SERP0856 | pflA | SERP0856 | SERP2365 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.438 |
SERP0856 | pflB | SERP0856 | SERP2366 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.942 |
bioB | pflA | SERP2347 | SERP2365 | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.428 |
lacR | SERP0516 | SERP1796 | SERP0516 | Lactose phosphotransferase system repressor; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer (By similarity). | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.767 |
lacR | pflA | SERP1796 | SERP2365 | Lactose phosphotransferase system repressor; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer (By similarity). | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.562 |
lacR | pflB | SERP1796 | SERP2366 | Lactose phosphotransferase system repressor; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer (By similarity). | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.511 |
narH | nirD | SERP1986 | SERP1989 | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to EGAD:30823; match to protein family HMM PF00355. | 0.992 |
narH | pflA | SERP1986 | SERP2365 | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.447 |
nirD | narH | SERP1989 | SERP1986 | Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to EGAD:30823; match to protein family HMM PF00355. | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | 0.992 |
nirD | pflA | SERP1989 | SERP2365 | Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to EGAD:30823; match to protein family HMM PF00355. | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.552 |
nirD | pflB | SERP1989 | SERP2366 | Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to EGAD:30823; match to protein family HMM PF00355. | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.433 |