STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqo-4Malate:quinone oxidoreductase; Identified by similarity to EGAD:9906; match to protein family HMM TIGR01320. (494 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Identified by similarity to EGAD:21870; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
  
 
 0.928
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.928
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.916
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.910
SERP1265
NADP-dependent malic enzyme, putative; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.
  
 
 0.908
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.821
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to EGAD:20751; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.814
argH
Argininosuccinate lyase; Identified by similarity to EGAD:108136; match to protein family HMM PF00206; match to protein family HMM TIGR00838.
    
 0.809
gltD
Glutamate synthase, small subunit; Identified by match to protein family HMM PF00070; match to protein family HMM TIGR01317.
    
  0.805
purB
Adenylosuccinate lyase; Identified by similarity to EGAD:15453; match to protein family HMM PF00206; match to protein family HMM TIGR00928.
     
  0.800
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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