node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cas2 | hsdM | SERP2462 | SERP2472 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. | 0.451 |
cas2 | hsdR | SERP2462 | SERP2474 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family. | 0.466 |
cas2 | rlmH | SERP2462 | SERP2529 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.495 |
copB | rlmH | SERP2438 | SERP2529 | Cation-transporting ATPase, E1-E2 family; Involved in copper transport. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.506 |
hsdM | cas2 | SERP2472 | SERP2462 | Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.451 |
hsdM | hsdR | SERP2472 | SERP2474 | Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family. | 0.998 |
hsdM | rlmH | SERP2472 | SERP2529 | Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.729 |
hsdR | cas2 | SERP2474 | SERP2462 | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family. | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.466 |
hsdR | hsdM | SERP2474 | SERP2472 | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family. | Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. | 0.998 |
hsdR | rlmH | SERP2474 | SERP2529 | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.763 |
mecI | mecR1 | SERP2519 | SERP2520 | Methicillin-resistance regulatory protein MecI; Identified by similarity to EGAD:6173; match to protein family HMM PF03965. | Methicillin-resistance regulatory protein MecR1; Penicillin-interactive protein and potential antirepressor. | 0.999 |
mecI | rlmH | SERP2519 | SERP2529 | Methicillin-resistance regulatory protein MecI; Identified by similarity to EGAD:6173; match to protein family HMM PF03965. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.596 |
mecR1 | mecI | SERP2520 | SERP2519 | Methicillin-resistance regulatory protein MecR1; Penicillin-interactive protein and potential antirepressor. | Methicillin-resistance regulatory protein MecI; Identified by similarity to EGAD:6173; match to protein family HMM PF03965. | 0.999 |
mecR1 | rlmH | SERP2520 | SERP2529 | Methicillin-resistance regulatory protein MecR1; Penicillin-interactive protein and potential antirepressor. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.521 |
rlmH | cas2 | SERP2529 | SERP2462 | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.495 |
rlmH | copB | SERP2529 | SERP2438 | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Cation-transporting ATPase, E1-E2 family; Involved in copper transport. | 0.506 |
rlmH | hsdM | SERP2529 | SERP2472 | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. | 0.729 |
rlmH | hsdR | SERP2529 | SERP2474 | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family. | 0.763 |
rlmH | mecI | SERP2529 | SERP2519 | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Methicillin-resistance regulatory protein MecI; Identified by similarity to EGAD:6173; match to protein family HMM PF03965. | 0.596 |
rlmH | mecR1 | SERP2529 | SERP2520 | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Methicillin-resistance regulatory protein MecR1; Penicillin-interactive protein and potential antirepressor. | 0.521 |