STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPG16838.1Stage V sporulation protein T; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)    
Predicted Functional Partners:
OPG16704.1
Sporulation transcriptional regulator SpoIIID; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.824
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.810
OPG16480.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.805
OPG16264.1
Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.799
OPG16619.1
Stage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.797
OPG16739.1
Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.795
OPG16212.1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.795
OPG16129.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.795
OPG16455.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   
 0.790
gpr
GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.785
Your Current Organism:
Acidibacillus ferrooxidans
NCBI taxonomy Id: 1765683
Other names: A. ferrooxidans, Alicyclobacillaceae bacterium ITV01, Alicyclobacillaceae bacterium SLC40, Firmicutes bacterium BSH1, Firmicutes bacterium MCF99, Gram-positive iron-oxidizing acidophile G1, Gram-positive iron-oxidizing acidophile SLC66, bacterium GS1, strain SLC66
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