node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceF | gcvH1 | FTT_1484c | FTT_0408 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.501 |
aceF | gcvH2 | FTT_1484c | FTT_0812 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.501 |
aceF | gcvP1 | FTT_1484c | FTT_0409 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.881 |
aceF | gcvP2 | FTT_1484c | FTT_0410 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Similar to Q83B09 Putative glycine cleavage system P protein, subunit 2 from Coxiella burnetii (491 aa). FASTA: opt: 2055 Z-score: 2482.9 E(): 2.1e-130 Smith-Waterman score: 2055; 63.071identity in 482 aa overlap. | 0.957 |
aceF | gcvT | FTT_1484c | FTT_0407 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage complex protein T (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.991 |
aceF | gdh | FTT_1484c | FTT_0380c | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Transposase, fragment; ISFtu1 12bp terminal inverted repeat; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.411 |
aceF | glnA | FTT_1484c | FTT_0196c | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Similar to AAO90051 (Q83E31) Glutamine synthetase from Coxiella burnetti (359 aa). FASTA: opt: 1369 Z-score: 1705.1 E(): 4.4e-87 Smith-Waterman score: 1369; 59.226 identity in 336 aa overlap. | 0.457 |
aceF | glyA | FTT_1484c | FTT_1241 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.771 |
aceF | lpd | FTT_1484c | FTT_1483c | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Transposase, fragement; 9 bp terminal inverse repeat. | 0.999 |
gcvH1 | aceF | FTT_0408 | FTT_1484c | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.501 |
gcvH1 | gcvH2 | FTT_0408 | FTT_0812 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.907 |
gcvH1 | gcvP1 | FTT_0408 | FTT_0409 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
gcvH1 | gcvP2 | FTT_0408 | FTT_0410 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Similar to Q83B09 Putative glycine cleavage system P protein, subunit 2 from Coxiella burnetii (491 aa). FASTA: opt: 2055 Z-score: 2482.9 E(): 2.1e-130 Smith-Waterman score: 2055; 63.071identity in 482 aa overlap. | 0.998 |
gcvH1 | gcvT | FTT_0408 | FTT_0407 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage complex protein T (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH1 | gdh | FTT_0408 | FTT_0380c | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Transposase, fragment; ISFtu1 12bp terminal inverted repeat; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.802 |
gcvH1 | glnA | FTT_0408 | FTT_0196c | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Similar to AAO90051 (Q83E31) Glutamine synthetase from Coxiella burnetti (359 aa). FASTA: opt: 1369 Z-score: 1705.1 E(): 4.4e-87 Smith-Waterman score: 1369; 59.226 identity in 336 aa overlap. | 0.814 |
gcvH1 | glyA | FTT_0408 | FTT_1241 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.945 |
gcvH1 | lpd | FTT_0408 | FTT_1483c | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Transposase, fragement; 9 bp terminal inverse repeat. | 0.942 |
gcvH2 | aceF | FTT_0812 | FTT_1484c | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.501 |
gcvH2 | gcvH1 | FTT_0812 | FTT_0408 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.907 |