STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmpTSimilar to TPMT_PSESJ Thiopurine S-methyltransferase from Pseudomonas syringae (218 aa). FASTA: opt: 370 z-score: 455.2 E(): 1.7e-17 Smith-Waterman score: 370; 35.165 identity in 182 aa overlap; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. (226 aa)    
Predicted Functional Partners:
FTT_0360
Similar to Q82V84 Short-chain dehydrogenase/reductase (SDR) superfamily from Nitrosomonas europaea (279 aa). FASTA: opt: 829 Z-score: 982.8 E(): 7.5e-47 Smith-Waterman score: 829; 49.632 identity in 272 aa overlap ORF ftt0360; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.779
slt
Similar to Q88L07 Soluble lytic transglycosylase, putative from Pseudomonas putida (657 aa). FASTA: opt: 596 Z-score: 646.0 E(): 3.9e-28 Smith-Waterman score: 819; 27.822 identity in 629 aa overlap.
   
  
 0.715
bamB
Conserved hypothetical lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
      
 0.703
lptE
Hypothetical lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
      
 0.698
pyrC
Dihydroorotase; Similar to Q8P8I4 Dihydroorotase from Xanthomonas campestris (449 aa). FASTA: opt: 1640 z-score: 1944.6 E(): 1.8e-100 Smith-Waterman score: 1640; 56.054 identity in 446 aa overlap.
  
    0.550
FTT_0293
Hypothetical membrane protein; Similar to Q88LA6 Von Willebrand factor type A domain protein from Pseuodmonas putida (358 aa). FASTA: opt: 905 Z-score: 1015.4 E(): 1.1e-48 Smith-Waterman score: 905; 45.122 identity in 328 aa overlap ORF ftt0293.
 
 
 
 0.459
FTT_0292
Similar to Q8D3W9 Conserved hypothetical protein from Vibrio vulnificus (156 aa). FASTA: opt: 228 Z-score: 276.8 E(): 1.5e-07 Smith-Waterman score: 228; 28.481 identity in 158 aa overlap ORF ftt0292.
 
 
 
 0.450
FTT_1534c
Similar to Q9ZNS0 Putative sugar transporter from Aribdopsis thaliana (508 aa). FASTA: opt: 409 Z-score: 463.9 E(): 5.5e-18 Smith-Waterman score: 499; 27.171 identity in 449 aa overlap. Contains a frameshift and a possible internal deletion of 50 aa after aa 199 ORF ftt1533c; Belongs to the NAPRTase family.
  
   
 0.450
coq7
Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
  
 
 0.428
Your Current Organism:
Francisella tularensis SCHUS4
NCBI taxonomy Id: 177416
Other names: F. tularensis subsp. tularensis SCHU S4, Francisella tularensis Biovar A str. SCHU S4, Francisella tularensis Biovar A str. Schu 4, Francisella tularensis subsp. tularensis SCHU S4, Francisella tularensis subsp. tularensis Schu 4, Francisella tularensis subsp. tularensis str. SCHU S4, Francisella tularensis subsp. tularensis strain SCHU S4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.