STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DP0224Probable precorrin-3B C17-methyltransferase (CobJ). (256 aa)    
Predicted Functional Partners:
DP0222
Probable precorrin-4 C11-methyltransferase (CobM).
 
 0.999
DP0223
Probable cobalamin biosynthesis protein (CbiG).
  
 0.999
DP0219
Probable precorrin-8X methylmutase (CobH).
  
 0.998
DP0221
Probable precorrin-6Y C5,15-methyltransferase (CobL).
 
  
 0.998
DP0211
Probable precorrin-2 C20-methyltransferase (CobI); Belongs to the precorrin methyltransferase family.
  
 0.997
cobQ
Related to aminotransferase and cobyric acid synthase (CobD and CobQ); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.993
cbiD
Probable cobalamin biosynthesis protein (CbiD); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.983
cbiA
Probable cobyrinic acid A,C-diamide synthase (CobB); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.966
cobS
Related to cobalamin synthase (CobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.911
DP0212
Probable cobalt chelatase, chain A.
 
  
 0.868
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
Server load: low (26%) [HD]