node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DP0802 | DP2214 | DP0802 | DP2214 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | 0.884 |
DP0802 | DP2942 | DP0802 | DP2942 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Conserved hypothetical protein. | 0.614 |
DP0802 | lpxA | DP0802 | DP2943 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.838 |
DP0802 | lpxB | DP0802 | DP1936 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Related to lipid-A-disaccharide synthase (LpxB); Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.858 |
DP0802 | lpxC | DP0802 | DP1939 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Probable UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.862 |
DP0802 | lpxD | DP0802 | DP2945 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Probable UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.863 |
DP0802 | lpxK | DP0802 | DP1938 | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | Related to tetraacyldisaccharide 4'-kinase (LpxK); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.879 |
DP0920 | lpxB | DP0920 | DP1936 | Probable methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Related to lipid-A-disaccharide synthase (LpxB); Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.901 |
DP1937 | DP2942 | DP1937 | DP2942 | Hypothetical protein. | Conserved hypothetical protein. | 0.913 |
DP1937 | lpxB | DP1937 | DP1936 | Hypothetical protein. | Related to lipid-A-disaccharide synthase (LpxB); Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.903 |
DP2214 | DP0802 | DP2214 | DP0802 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.884 |
DP2214 | DP2942 | DP2214 | DP2942 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Conserved hypothetical protein. | 0.642 |
DP2214 | lpxA | DP2214 | DP2943 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.841 |
DP2214 | lpxB | DP2214 | DP1936 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Related to lipid-A-disaccharide synthase (LpxB); Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.850 |
DP2214 | lpxC | DP2214 | DP1939 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Probable UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.851 |
DP2214 | lpxD | DP2214 | DP2945 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Probable UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.848 |
DP2214 | lpxK | DP2214 | DP1938 | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | Related to tetraacyldisaccharide 4'-kinase (LpxK); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.854 |
DP2942 | DP0802 | DP2942 | DP0802 | Conserved hypothetical protein. | Related to polysialic acid capsule expression protein (KpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.614 |
DP2942 | DP1937 | DP2942 | DP1937 | Conserved hypothetical protein. | Hypothetical protein. | 0.913 |
DP2942 | DP2214 | DP2942 | DP2214 | Conserved hypothetical protein. | Related to 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | 0.642 |