STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobDRelated to cobalamin biosynthesis protein (CobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (330 aa)    
Predicted Functional Partners:
DP1953
Related to bifunctional cobalamin biosynthesis protein (CobP); Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 
 0.994
cobQ
Related to aminotransferase and cobyric acid synthase (CobD and CobQ); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.984
DP2168
Probable COB(I)alamin adenosyltransferase (CobO); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.971
cobS
Related to cobalamin synthase (CobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
 0.965
cobT
Related to nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (CobT); Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.935
DP0219
Probable precorrin-8X methylmutase (CobH).
 
  
 0.917
DP0221
Probable precorrin-6Y C5,15-methyltransferase (CobL).
 
  
 0.904
cbiA
Probable cobyrinic acid A,C-diamide synthase (CobB); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.883
cbiA-2
Probable cobyrinic acid A,C-diamide synthase (CobB); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.855
DP0224
Probable precorrin-3B C17-methyltransferase (CobJ).
 
   
 0.844
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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