STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1161Hypothetical protein with conserved Forkhead-associated (FHA) domain; Unclassified. (100 aa)    
Predicted Functional Partners:
rpl40e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL40 family.
    
  0.815
PAE2648
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Energy metabolism; Glycolysis/gluconeogenesis.
  
 
 0.765
PAE1162
Hypothetical protein.
       0.714
PAE2904
Exonuclease sbcD, conjectural; DNA metabolism; DNA replication, recombination, and repair.
  
 
 0.685
PAE2280
Conserved hypothetical protein.
 
 
 0.650
PAE2905
Purine NTPase, probable; Unclassified.
 
 
 0.623
PAE1159
Hypothetical protein.
       0.563
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
 
 0.478
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
 
   
 0.423
PAE2024
Conserved hypothetical protein.
  
 
 0.414
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.