node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAE0309 | PAE0741 | PAE0309 | PAE0741 | Chlorohydrolase, conjectural; Unclassified. | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.506 |
PAE0309 | PAE2158 | PAE0309 | PAE2158 | Chlorohydrolase, conjectural; Unclassified. | Fuculose-1-phosphate aldolase (fucA); Energy metabolism; Sugars. | 0.483 |
PAE0309 | eif5a | PAE0309 | PAE3337 | Chlorohydrolase, conjectural; Unclassified. | Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.427 |
PAE0309 | guaA | PAE0309 | PAE3369 | Chlorohydrolase, conjectural; Unclassified. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.641 |
PAE0309 | mtnP | PAE0309 | PAE3338 | Chlorohydrolase, conjectural; Unclassified. | Purine nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.598 |
PAE0741 | PAE0309 | PAE0741 | PAE0309 | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Chlorohydrolase, conjectural; Unclassified. | 0.506 |
PAE0741 | PAE2071 | PAE0741 | PAE2071 | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Phosphoribosyl transferase; Unclassified. | 0.644 |
PAE0741 | PAE2158 | PAE0741 | PAE2158 | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Fuculose-1-phosphate aldolase (fucA); Energy metabolism; Sugars. | 0.821 |
PAE0741 | eif5a | PAE0741 | PAE3337 | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.448 |
PAE0741 | mtnP | PAE0741 | PAE3338 | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Purine nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.688 |
PAE0741 | speE | PAE0741 | PAE1203 | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to norspermidine and 1,3- diaminopropane to yield norspermine, and to spermidine to yield thermospermine. It can also synthesize thermospermine from putrescine (1,4-diaminobutane) and caldop [...] | 0.616 |
PAE1476 | mtnP | PAE1476 | PAE3338 | Purines, pyrimidines, nucleosides, and nucleotides; Salvage of nucleosides and nucleotides. | Purine nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.926 |
PAE1476 | speE | PAE1476 | PAE1203 | Purines, pyrimidines, nucleosides, and nucleotides; Salvage of nucleosides and nucleotides. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to norspermidine and 1,3- diaminopropane to yield norspermine, and to spermidine to yield thermospermine. It can also synthesize thermospermine from putrescine (1,4-diaminobutane) and caldop [...] | 0.900 |
PAE2071 | PAE0741 | PAE2071 | PAE0741 | Phosphoribosyl transferase; Unclassified. | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.644 |
PAE2071 | PAE2158 | PAE2071 | PAE2158 | Phosphoribosyl transferase; Unclassified. | Fuculose-1-phosphate aldolase (fucA); Energy metabolism; Sugars. | 0.608 |
PAE2071 | eif5a | PAE2071 | PAE3337 | Phosphoribosyl transferase; Unclassified. | Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.493 |
PAE2071 | guaA | PAE2071 | PAE3369 | Phosphoribosyl transferase; Unclassified. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.999 |
PAE2071 | mtnP | PAE2071 | PAE3338 | Phosphoribosyl transferase; Unclassified. | Purine nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.645 |
PAE2158 | PAE0309 | PAE2158 | PAE0309 | Fuculose-1-phosphate aldolase (fucA); Energy metabolism; Sugars. | Chlorohydrolase, conjectural; Unclassified. | 0.483 |
PAE2158 | PAE0741 | PAE2158 | PAE0741 | Fuculose-1-phosphate aldolase (fucA); Energy metabolism; Sugars. | Translation initiation factor aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.821 |