node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NEDG_00424 | NEDG_00599 | A0A177ELU1 | A0A177ECK8 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.851 |
NEDG_00424 | NEDG_01060 | A0A177ELU1 | A0A177EBP3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | S-phase kinase-associated protein 1. | 0.678 |
NEDG_00424 | NEDG_01339 | A0A177ELU1 | A0A177EC07 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Thioredoxin reductase (NADPH). | 0.704 |
NEDG_00424 | NEDG_01865 | A0A177ELU1 | A0A177EHZ2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | GATA-type domain-containing protein. | 0.664 |
NEDG_00424 | NEDG_01871 | A0A177ELU1 | A0A177EGL6 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase. | 0.960 |
NEDG_00424 | NEDG_01880 | A0A177ELU1 | A0A177EHC3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Elongation of fatty acids protein. | 0.884 |
NEDG_00424 | NEDG_01892 | A0A177ELU1 | A0A177EGX1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | GATA-type domain-containing protein. | 0.664 |
NEDG_00424 | NEDG_01896 | A0A177ELU1 | A0A177EJ17 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Glycos_transf_1 domain-containing protein. | 0.904 |
NEDG_00424 | NEDG_01990 | A0A177ELU1 | A0A177EF21 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Uncharacterized protein. | 0.664 |
NEDG_00424 | NEDG_02057 | A0A177ELU1 | A0A177EKT2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Response regulatory domain-containing protein. | 0.804 |
NEDG_00599 | NEDG_00424 | A0A177ECK8 | A0A177ELU1 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.851 |
NEDG_00599 | NEDG_01339 | A0A177ECK8 | A0A177EC07 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Thioredoxin reductase (NADPH). | 0.953 |
NEDG_00599 | NEDG_01865 | A0A177ECK8 | A0A177EHZ2 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | GATA-type domain-containing protein. | 0.640 |
NEDG_00599 | NEDG_01871 | A0A177ECK8 | A0A177EGL6 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase. | 0.878 |
NEDG_00599 | NEDG_01880 | A0A177ECK8 | A0A177EHC3 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Elongation of fatty acids protein. | 0.946 |
NEDG_00599 | NEDG_01892 | A0A177ECK8 | A0A177EGX1 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | GATA-type domain-containing protein. | 0.640 |
NEDG_00599 | NEDG_01896 | A0A177ECK8 | A0A177EJ17 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Glycos_transf_1 domain-containing protein. | 0.959 |
NEDG_00599 | NEDG_01990 | A0A177ECK8 | A0A177EF21 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Uncharacterized protein. | 0.640 |
NEDG_00599 | NEDG_02057 | A0A177ECK8 | A0A177EKT2 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Response regulatory domain-containing protein. | 0.744 |
NEDG_01060 | NEDG_00424 | A0A177EBP3 | A0A177ELU1 | S-phase kinase-associated protein 1. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.678 |