STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEDG_00424Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (270 aa)    
Predicted Functional Partners:
NEDG_01871
17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase.
   
 0.960
NEDG_01896
Glycos_transf_1 domain-containing protein.
    
 0.904
NEDG_01880
Elongation of fatty acids protein.
    
 0.884
NEDG_00599
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
     
 0.851
NEDG_02057
Response regulatory domain-containing protein.
   
 
 0.804
NEDG_01339
Thioredoxin reductase (NADPH).
   
 
 0.704
NEDG_01060
S-phase kinase-associated protein 1.
    
 
 0.678
NEDG_01990
Uncharacterized protein.
    
 0.664
NEDG_01892
GATA-type domain-containing protein.
    
 0.664
NEDG_01865
GATA-type domain-containing protein.
    
 0.664
Your Current Organism:
Nematocida displodere
NCBI taxonomy Id: 1805483
Other names: N. displodere, Nematocida displodere Luallen et al. 2016, Nematocida sp. JUm2807
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