node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB79232.1 | KXB79362.1 | HMPREF1862_01848 | HMPREF1862_01987 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | 0.513 |
KXB79232.1 | KXB80534.1 | HMPREF1862_01848 | HMPREF1862_01217 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA gyrase/topoisomerase IV, A subunit; KEGG: mcu:HMPREF0573_11790 1.0e-245 gyrA; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | 0.495 |
KXB79232.1 | KXB81532.1 | HMPREF1862_01848 | HMPREF1862_00508 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | HRDC domain protein; KEGG: bcv:Bcav_2897 5.8e-165 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.547 |
KXB79232.1 | ftsZ | HMPREF1862_01848 | HMPREF1862_01076 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.581 |
KXB79232.1 | gyrB | HMPREF1862_01848 | HMPREF1862_01988 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.813 |
KXB79362.1 | KXB79232.1 | HMPREF1862_01987 | HMPREF1862_01848 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.513 |
KXB79362.1 | KXB79374.1 | HMPREF1862_01987 | HMPREF1862_01999 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.448 |
KXB79362.1 | dnaA | HMPREF1862_01987 | HMPREF1862_00670 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.417 |
KXB79362.1 | dnaK | HMPREF1862_01987 | HMPREF1862_01035 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.579 |
KXB79362.1 | ftsZ | HMPREF1862_01987 | HMPREF1862_01076 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.571 |
KXB79362.1 | gyrB | HMPREF1862_01987 | HMPREF1862_01988 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
KXB79362.1 | recF | HMPREF1862_01987 | HMPREF1862_01998 | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.455 |
KXB79374.1 | KXB79362.1 | HMPREF1862_01999 | HMPREF1862_01987 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: mcu:HMPREF0573_10684 0. gyrAS; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | 0.448 |
KXB79374.1 | KXB80534.1 | HMPREF1862_01999 | HMPREF1862_01217 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase/topoisomerase IV, A subunit; KEGG: mcu:HMPREF0573_11790 1.0e-245 gyrA; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | 0.448 |
KXB79374.1 | KXB81532.1 | HMPREF1862_01999 | HMPREF1862_00508 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | HRDC domain protein; KEGG: bcv:Bcav_2897 5.8e-165 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
KXB79374.1 | dnaA | HMPREF1862_01999 | HMPREF1862_00670 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.997 |
KXB79374.1 | ftsZ | HMPREF1862_01999 | HMPREF1862_01076 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.429 |
KXB79374.1 | gyrB | HMPREF1862_01999 | HMPREF1862_01988 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.896 |
KXB79374.1 | recF | HMPREF1862_01999 | HMPREF1862_01998 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.978 |
KXB80534.1 | KXB79232.1 | HMPREF1862_01217 | HMPREF1862_01848 | DNA gyrase/topoisomerase IV, A subunit; KEGG: mcu:HMPREF0573_11790 1.0e-245 gyrA; DNA topoisomerase K02469; Psort location: Cytoplasmic, score: 9.97. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.495 |