STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0142Asparaginase; Function Code: 5.6 Central Intermediary Metabolism: Other. (306 aa)    
Predicted Functional Partners:
PF2047
L-asparaginase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
    
 0.941
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.933
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Function Code: 9.4 Purines, Pyrimidines, Nucleosides and Nucleotides: Pyrimidine ribonucleotide biosynthesis; (pyrB).
 
  
  0.914
PF0792
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
     
 0.914
PF1071
Asparagine synthetase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
     
 0.914
PF0522
Aspartate transaminase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
   
 0.905
PF1702
Aspartate aminotransferase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family; (aspB-2).
   
 0.905
argG
Argininosuccinate synthase; Function Code: 1.4 Amino Acid Biosynthesis: Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.900
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
    
  0.900
PF0980
Putative aspartate racemase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
    
  0.900
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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