STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmSGlucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (598 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase i; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
 
 
 0.973
carB
Carbamoyl-phosphate synthase large chain (glutamine-hydrolysing); Function Code: 9.4 Purines, Pyrimidines, Nucleosides and Nucleotides: Pyrimidine ribonucleotide biosynthesis.
   
 0.966
PF0362
Glucosamine-fructose-6-phosphate aminotransferase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens.
 
 
0.964
purQ
Phosphoribosylformylglycinamidine synthase (FGAM synthase i); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is tho [...]
    
 0.950
glmM
Phospho-sugar mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.950
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.947
carA
Carbamoyl-phosphate synthase, small (or glutamine) subunit; Function Code: 9.4 Purines, Pyrimidines, Nucleosides and Nucleotides: Pyrimidine ribonucleotide biosynthesis; (carA); Belongs to the CarA family.
    
 0.941
PF1738
Sugar kinase; Function Code: 6.9 Energy Metabolism: Sugars; Belongs to the carbohydrate kinase PfkB family.
 
 0.930
PF1458
Sugar kinase; Function Code: 6.9 Energy Metabolism: Sugars; Belongs to the carbohydrate kinase PfkB family.
 
 0.929
PF1852
Glutamate synthase small subunit; Function Code: 5.6 Central Intermediary Metabolism: Other.
    
 0.917
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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