node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | cysS | PF1380 | PF1024 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | 0.854 |
argS | ileS | PF1380 | PF1096 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.965 |
argS | leuS | PF1380 | PF0890 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.924 |
argS | pheS | PF1380 | PF0989 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase, alpha-subunit; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.839 |
argS | pheT | PF1380 | PF0990 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase beta-chain; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | 0.891 |
argS | serS | PF1380 | PF1204 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.878 |
argS | trpS | PF1380 | PF0241 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | tryptophanyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.893 |
argS | tyrS | PF1380 | PF0862 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.889 |
argS | valS | PF1380 | PF0290 | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.890 |
cysS | argS | PF1024 | PF1380 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.854 |
cysS | ileS | PF1024 | PF1096 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.783 |
cysS | leuS | PF1024 | PF0890 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | leucyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.901 |
cysS | pheS | PF1024 | PF0989 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | phenylalanyl-tRNA synthetase, alpha-subunit; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.616 |
cysS | pheT | PF1024 | PF0990 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | phenylalanyl-tRNA synthetase beta-chain; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | 0.669 |
cysS | serS | PF1024 | PF1204 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.844 |
cysS | trpA | PF1024 | PF1705 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | Tryptophan synthetase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family. | 0.421 |
cysS | trpS | PF1024 | PF0241 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | tryptophanyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.780 |
cysS | tyrS | PF1024 | PF0862 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.808 |
cysS | valS | PF1024 | PF0290 | cysteinyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.914 |
ileS | argS | PF1096 | PF1380 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.965 |