STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppaInorganic pyrophosphatase (pyrophosphate phospho-hydrolase); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (178 aa)    
Predicted Functional Partners:
PF0178
ATPase subunit K; Function Code: 6.3 Energy Metabolism: ATP-proton motive force interconversion.
  
 
 0.962
atpD
ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.939
atpA
ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family.
   
 
 0.937
atpB
ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
   
 
 0.934
PF0177
ATPase subunit I; Function Code: 6.3 Energy Metabolism: ATP-proton motive force interconversion; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.918
atpE
ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.912
rpl13
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.911
atpF
ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.908
PF0176
ATPase subunit B; Function Code: 6.3 Energy Metabolism: ATP-proton motive force interconversion.
     
  0.900
atpC
ATPase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
     
  0.900
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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